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Non-invasive shock wave stimulated periosteum for bone tissue engineering
This work proposes that ESW-therapy can be used as a non-invasive, inexpensive, and rapid method for stimulating cambium cell proliferation, and investigates the use of these cells for orthotopic bone growth.
Just four days after application of ESWs, there was a significant 3- to 6-fold increase in cambium cell number and thickness. The most effective treatment of those tested was high dose ESW applied to the tibia.
The results successfully demonstrated the efficacy of ESW-stimulated periosteum for bone tissue engineering.
might be able to manipulate the cambium cells in the lower periosteum layer to grow in thickness from proliferation.
This work proposes that ESW-therapy can be used as a non-invasive, inexpensive, and rapid method for stimulating cambium cell proliferation, and investigates the use of these cells for orthotopic bone growth.
Just four days after application of ESWs, there was a significant 3- to 6-fold increase in cambium cell number and thickness. The most effective treatment of those tested was high dose ESW applied to the tibia.
The results successfully demonstrated the efficacy of ESW-stimulated periosteum for bone tissue engineering.
might be able to manipulate the cambium cells in the lower periosteum layer to grow in thickness from proliferation.
- ESW application even at a lower energy flex density does cause the periosteum to grow more bone from cambium cell thickness increase, which means we will grow taller by a little using this non-invasive method.
- The problem is that the ESW causes osteogeneis but not chondrogenesis, which is what we should really be focusing on to get grow taller by a much larger amount. Osteogenesis might increase our height by 1 cms maximum (a personal guess) but Chondrogenesis could lead to hypertrophy and multiple inches in height increase.