JFL at anyone not using Accutane

[Fear]

Daily low-dose isotretinoin is KING.
Zero blackheads, zero wrinkles, absolutely flawless skin.
Nothing comes close to its ability to grant a perfect and glowing complexion.

JFL at Retin-A, waiting 30 minutes for your skin to dry, layering correctly with moisturizers, etc. Topical retinoids, especially that cheap-ass shit they sell on AllDayChemist, are a SIDESHOW. Barely one step above cope, on roughly the same level as spraying Windex on pimples.

Frankly, Hoffmann-La Roche should be given the Nobel Prize for Medicine, and then the whole award should be just cancelled forever, because no subsequent Nobels could POSSIBLY measure up. Cures for cancer, Alzheimer's, HIV -- MEANINGLESS.

B-b-but...

"Muh photosensitivity"
"Muh liver enzymes"
"Muh telomeres"
"Muh lifespan"

Shut the fuck up, pussy. Do you want skin that mogs a newborn you cuck? Then start popping those pills.

Think it’s too good to be true? Then you’re an idiot. Why do you think the healthcare system makes you jump through numerous, time-consuming, and expensive hoops to get your hands on this cheap and easily manufactured drug? Referral from a GP to a specialist, fucking around with benzoyl peroxide and clindamycin and other shitty topical treatments for months, that stupid pledge not to have sex, blood work costing thousands of dollars. It’s because it IS the cure – it is the FINAL SOLUTION. So why would they want you to have it? They don't. Society wants to keep its boot on your head so you'll never not know the taste of dirt, so they can keep milking you and fleecing you with bullshit treatments forever. They don’t want you to ascend.

So fuck them. And fuck you too if you think you don't need this miracle drug like you need air to breathe. Go ahead and waste your time with Pajeet Pharma's knockoff Retin-A.

Convenient, inexpensive, anti-wrinkle, anti-acne, pore-shrinking, improves skin tone, thickness, elasticity... WHAT MORE DO YOU WANT?

 

[needsolution]

Sorry mods i have to


Didnt read

 

[her]

Just fuck up your liver theory.

 

[Deleted member 4675]

Just fuck up your liver theory.

wow, who cares if you have a nice healthy liver when u are a depressed incel?

 

[her]

wow, who cares if you have a nice healthy liver when u are a depressed incel?

Wow, who cares if you have a nice "healthy" skin when you are a depressed incel?

Retin-A does the same as Accutane without going systematic and fucking up your body.

 

[wristcel]

why does accutane help wrinkles? Doesn't it dry skin out thus increasing wrinkles?

ps - I've been cycling low dose accutane for years lol

 

[.👽.]

Does this or retin A removes blackheads?

 

[yang]

@benignice thoughts?

 

[benignice]

@benignice thoughts?

Amusingly incorrect to the point I assumed it was trolling.

 

[Nosecel]

Muh lifespan

Only on Looksmax.me

 

[Fear]

Retin-A does the same as Accutane without going systematic and fucking up your body.

If they did the same thing, then isotretinoin wouldn't have a reason to exist.

The side effect profile is eliminated by keeping the dose low.
In this way it is superior to the frequent dermatitis induced by tretinoin.

Does this or retin A removes blackheads?

Yes, isotretinoin obliterates blackheads.
This is stated explicitly in literally the second line of my post.

After 8 days of 10mg/day of isotretinoin, blackheads will begin to dry up and erupt from your nose.
After 13 days, your nose will be blackhead-free.
Retin-A cannot achieve this.

Amusingly incorrect to the point I assumed it was trolling.

An amusingly smug dismissal.
I've dealt with your type before.
Self-satisfied behind your feigned modesty.
Get off your high horse. You don't have the experience, expertise, or evidence to prove me wrong.

Oral isotretinoin as part of the treatment of cutaneous aging.
https://www.ncbi.nlm.nih.gov/pubmed/10886272

All patients treated with oral isotretinoin noted improvement in wrinkles, thickness and color of the skin, size of pores, skin elasticity, tone, and reduction in pigmented lesions and mottled hyperpigmentation.

Oral isotretinoin in photoaging: clinical and histopathological evidence of efficacy of an off-label indication.
https://www.ncbi.nlm.nih.gov/pubmed/18811602

The increase in the amount of collagen fibres was statistically significant

A pattern pointing toward a decrease in the number of elastic fibres was found

Additionally, there was improvement in the general aspect of the skin, regarding texture, wrinkles depth and skin coloration.

Oral isotretinoin in photoaging: objective histological evidence of efficacy and durability.
https://www.ncbi.nlm.nih.gov/pubmed/26375216

We observed an increase in collagen density .... [and] an increase in the density of elastic fibers

Clinically, patients, as well as the researching and the assessor physicians, noticed improvement in skin quality.

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study
https://www.ncbi.nlm.nih.gov/pubmed/24168514

Scores using the Dermatology Quality of Life Index were higher for isotretinoin versus tretinoin.


A randomized and controlled trial about the use of oral isotretinoin for photoaging.
https://www.ncbi.nlm.nih.gov/pubmed/20465648

Isotretinoin shows a major reduction in p53 epidermal expression.
p53 has been identified to induce skin aging, with its chronic activation associated with a loss of subcutaneous fat and dry skin.
Tretinoin, meanwhile, increases the expression of p53.

 

[Uglyandfat]

Daily low-dose isotretinoin is KING.
Zero blackheads, zero wrinkles, absolutely flawless skin.
Nothing comes close to its ability to grant a perfect and glowing complexion.

JFL at Retin-A, waiting 30 minutes for your skin to dry, layering correctly with moisturizers, etc. Topical retinoids, especially that cheap-ass shit they sell on AllDayChemist, are a SIDESHOW. Barely one step above cope, on roughly the same level as spraying Windex on pimples.

Frankly, Hoffmann-La Roche should be given the Nobel Prize for Medicine, and then the whole award should be just cancelled forever, because no subsequent Nobels could POSSIBLY measure up. Cures for cancer, Alzheimer's, HIV -- MEANINGLESS.

B-b-but...

"Muh photosensitivity"
"Muh liver enzymes"
"Muh telomeres"
"Muh lifespan"

Shut the fuck up, pussy. Do you want skin that mogs a newborn you cuck? Then start popping those pills.

Think it’s too good to be true? Then you’re an idiot. Why do you think the healthcare system makes you jump through numerous, time-consuming, and expensive hoops to get your hands on this cheap and easily manufactured drug? Referral from a GP to a specialist, fucking around with benzoyl peroxide and clindamycin and other shitty topical treatments for months, that stupid pledge not to have sex, blood work costing thousands of dollars. It’s because it IS the cure – it is the FINAL SOLUTION. So why would they want you to have it? They don't. Society wants to keep its boot on your head so you'll never not know the taste of dirt, so they can keep milking you and fleecing you with bullshit treatments forever. They don’t want you to ascend.

So fuck them. And fuck you too if you think you don't need this miracle drug like you need air to breathe. Go ahead and waste your time with Pajeet Pharma's knockoff Retin-A.

Convenient, inexpensive, anti-wrinkle, anti-acne, pore-shrinking, improves skin tone, thickness, elasticity... WHAT MORE DO YOU WANT?

where can i get acutine? I had no idea it did more than just fix acne lol my pores and shit are so bad i need thatr shit rn

 

[JustTrynaGrow]

Just stunt your growth theory

 

[Deleted member 2756]

Just stunt your growth theory

 

[Dicklet.4.3]

lol

 

[Deleted member 4545]

Jew spotted

 

[Deleted member 2527]

it fucks up your hair

not only am i sure it caused hair loss for me but it also makes it super dry and shitty quality

you are switching good skin for shit hair

 

[Gonion]

Isotretinoin shows a major reduction in p53 epidermal expression.
p53 has been identified to induce skin aging, with its chronic activation associated with a loss of subcutaneous fat and dry skin.
Tretinoin, meanwhile, increases the expression of p53.

Could this be one of the reasons why some people get loss of facial fat from retin a? Another reason may be the fact that vitamin a can mess with fat metabolism (doesn't isotretinoin increase serum triglycerides?) @benignice

 

[Deleted member 656]

An amusingly smug dismissal.
I've dealt with your type before.
Self-satisfied behind your feigned modesty.
Get off your high horse. You don't have the experience, expertise, or evidence to prove me wrong.

Imagine questioning the experience and expertise of an actual cosmetic chemist on a matter of skincare.

 

[Mrhaircut33]

Daily low-dose isotretinoin is KING.
Zero blackheads, zero wrinkles, absolutely flawless skin.
Nothing comes close to its ability to grant a perfect and glowing complexion.

JFL at Retin-A, waiting 30 minutes for your skin to dry, layering correctly with moisturizers, etc. Topical retinoids, especially that cheap-ass shit they sell on AllDayChemist, are a SIDESHOW. Barely one step above cope, on roughly the same level as spraying Windex on pimples.

Frankly, Hoffmann-La Roche should be given the Nobel Prize for Medicine, and then the whole award should be just cancelled forever, because no subsequent Nobels could POSSIBLY measure up. Cures for cancer, Alzheimer's, HIV -- MEANINGLESS.

B-b-but...

"Muh photosensitivity"
"Muh liver enzymes"
"Muh telomeres"
"Muh lifespan"

Shut the fuck up, pussy. Do you want skin that mogs a newborn you cuck? Then start popping those pills.

Think it’s too good to be true? Then you’re an idiot. Why do you think the healthcare system makes you jump through numerous, time-consuming, and expensive hoops to get your hands on this cheap and easily manufactured drug? Referral from a GP to a specialist, fucking around with benzoyl peroxide and clindamycin and other shitty topical treatments for months, that stupid pledge not to have sex, blood work costing thousands of dollars. It’s because it IS the cure – it is the FINAL SOLUTION. So why would they want you to have it? They don't. Society wants to keep its boot on your head so you'll never not know the taste of dirt, so they can keep milking you and fleecing you with bullshit treatments forever. They don’t want you to ascend.

So fuck them. And fuck you too if you think you don't need this miracle drug like you need air to breathe. Go ahead and waste your time with Pajeet Pharma's knockoff Retin-A.

Convenient, inexpensive, anti-wrinkle, anti-acne, pore-shrinking, improves skin tone, thickness, elasticity... WHAT MORE DO YOU WANT?

Just go bald and get anhedonia bro

 

[benignice]

An amusingly smug dismissal.
I've dealt with your type before.
Self-satisfied behind your feigned modesty.
Get off your high horse. You don't have the experience, expertise, or evidence to prove me wrong.

I wasn't going to bother answering this but quite frankly, I don't want other users thinking that isotretinoin should be their first port of call.
Theres a reason that you usually have to jump through so many hoops in order to get isotretinoin (and it's got sweet fuck all to do with a medical conspiracy- why would they do that? Pharma could make an absolute killing if it went to mass market and trust me, that's what they care about. Why would they pass off their potential profits to (rival) cosmetics companies you absolute walnut?) -it's a serious drug with some potentially serious side effects (even on low doses). You can absolutely get phenomenal skin without the use of isotretinoin, and to imply that its totally safe and should be the first port of call is beyond irresponsible.

And side note: not that my credentials make what I'm saying any more accurate, but as @Alarico8 pointed out, I work as a cosmetic chemist. So while I'm not prescribing isotretinoin, I do have a fair amount of experience with skincare.

Could this be one of the reasons why some people get loss of facial fat from retin a? Another reason may be the fact that vitamin a can mess with fat metabolism (doesn't isotretinoin increase serum triglycerides?) @benignice

Not sure about the loss of facial fat from tretinoin (in that when taken orally it can be a thing but I'm not sure how much of that would translate to topical use), but yes isotretinoin can increase serum triglycerides.

 

[middayshowers]

i took it and i don’t regret taking it, but if you’re on accutane while not struggling with moderate/severe acne you’re retarded ngl

 

[Deleted member 4612]

I'm already 24 and dont get acne anymore.

Retarded thread is retarded

 

[Seth Walsh]

Daily low-dose isotretinoin is KING.
Zero blackheads, zero wrinkles, absolutely flawless skin.
Nothing comes close to its ability to grant a perfect and glowing complexion.

JFL at Retin-A, waiting 30 minutes for your skin to dry, layering correctly with moisturizers, etc. Topical retinoids, especially that cheap-ass shit they sell on AllDayChemist, are a SIDESHOW. Barely one step above cope, on roughly the same level as spraying Windex on pimples.

Frankly, Hoffmann-La Roche should be given the Nobel Prize for Medicine, and then the whole award should be just cancelled forever, because no subsequent Nobels could POSSIBLY measure up. Cures for cancer, Alzheimer's, HIV -- MEANINGLESS.

B-b-but...

"Muh photosensitivity"
"Muh liver enzymes"
"Muh telomeres"
"Muh lifespan"

Shut the fuck up, pussy. Do you want skin that mogs a newborn you cuck? Then start popping those pills.

Think it’s too good to be true? Then you’re an idiot. Why do you think the healthcare system makes you jump through numerous, time-consuming, and expensive hoops to get your hands on this cheap and easily manufactured drug? Referral from a GP to a specialist, fucking around with benzoyl peroxide and clindamycin and other shitty topical treatments for months, that stupid pledge not to have sex, blood work costing thousands of dollars. It’s because it IS the cure – it is the FINAL SOLUTION. So why would they want you to have it? They don't. Society wants to keep its boot on your head so you'll never not know the taste of dirt, so they can keep milking you and fleecing you with bullshit treatments forever. They don’t want you to ascend.

So fuck them. And fuck you too if you think you don't need this miracle drug like you need air to breathe. Go ahead and waste your time with Pajeet Pharma's knockoff Retin-A.

Convenient, inexpensive, anti-wrinkle, anti-acne, pore-shrinking, improves skin tone, thickness, elasticity... WHAT MORE DO YOU WANT?

Going by research, Honestly accutane isn't King - that being said i'm Curious to Understand what is

 

[Gonion]

Not sure about the loss of facial fat from tretinoin (in that when taken orally it can be a thing but I'm not sure how much of that would translate to topical use), but yes isotretinoin can increase serum triglycerides.

On realself and reddit there are a lot of people complaining about loss of facial fat (that made them look older and uglier), and they didn't know about this problem before using it, so it can't be a nocebo effect.

Doctors of realself refuse to believe in this, but one doctor accepted this possibility saying that vitamin a affect fat metabolism.

My theory is that tretinoin can possibly cause fat cells apoptosis. What do you think? And do you personally use tretinoin?

 

[benignice]

On realself and reddit there are a lot of people complaining about loss of facial fat (that made them look older and uglier), and they didn't know about this problem before using it, so it can't be a nocebo effect.

Doctors of realself refuse to believe in this, but one doctor accepted this possibility saying that vitamin a affect fat metabolism.

My theory is that tretinoin can possibly cause fat cells apoptosis. What do you think? And do you personally use tretinoin?

Like I said, I don't know enough about it to comment either way. I do use tretinoin sometimes- my skin can't take it all the time but when it can, I do use it. Honestly though, even if I could use it all the time I probably wouldn't since trying out different formulas is such a massive part of my job.

 

[Gonion]

Like I said, I don't know enough about it to comment either way. I do use tretinoin sometimes- my skin can't take it all the time but when it can, I do use it. Honestly though, even if I could use it all the time I probably wouldn't since trying out different formulas is such a massive part of my job.

Thanks anyway. I've never used it and probably never will, other than for this problem also because in my opinion in the long term it will make you age faster because with the same amount of sunscreen now you will get less protection because of the photosensitivity induced by tretinoin. I don't think that exchange increased collagen production in the short-medium term for increased aging in the long term is a wise choice

 

[Fear]

Imagine questioning the experience and expertise of an actual cosmetic chemist on a matter of skincare.

Imagine being such a meek and deferent lemming that you think credentials are a substitute for an argument.

I don't care if he's a cosmetic chemist, and I mean that without disrespect; it just literally means nothing to me.
If anything, I wouldn't even bring it up if I were him, since everyone knows the cosmetic skincare industry is a unabashed scam, and the people working to pump out the same products with different names every year -- the majority of which don't even work or do anything special (if they did, the variety of offerings would shrink exponentially) -- are either stupid or deceitful.

In any event, what's important is this:
One should prove his point with reason or evidence, or butt out.
Because I don't suffer assertions that I am a liar or mistaken lightly.

I'm already 24 and dont get acne anymore.

Retarded thread is retarded

It's therefore inconceivable, then, that anyone else your age or older gets acne, or that there are possibly even other applications for this drug, right you solipsistic twit? Talk about retarded.

I wasn't going to bother answering this but quite frankly, I don't want other users thinking that isotretinoin should be their first port of call.
Theres a reason that you usually have to jump through so many hoops in order to get isotretinoin (and it's got sweet fuck all to do with a medical conspiracy- why would they do that? Pharma could make an absolute killing if it went to mass market and trust me, that's what they care about. Why would they pass off their potential profits to (rival) cosmetics companies you absolute walnut?) -it's a serious drug with some potentially serious side effects (even on low doses). You can absolutely get phenomenal skin without the use of isotretinoin, and to imply that its totally safe and should be the first port of call is beyond irresponsible.

I am aware that theirs is a profit motive. But in so stressing you are proving my point, because there is a much bigger killing to be made by peddling an endless series of inefficacious treatments than simply skipping to the cure.
Also, they know anything teratogenic or with the stigma of suicide lingering around it will not achieve mass penetration.

i took it and i don’t regret taking it, but if you’re on accutane while not struggling with moderate/severe acne you’re retarded ngl

Retarded?
No.
Visionary.

In the pursuit of perfection, nothing is off-limits.
I will do anything to claw the scraps of life and time from the hands of the diamond-toothed few.
The shadow of fortune will not claim me; I won't live the dying life again.

But perfection isn't good enough.
Life is a war, and I am here to win and keep on winning.
Over and over, and over again.

No one will stop me.

No one.

 

[Deleted member 656]

Imagine being such a meek and deferent lemming that you think credentials are a substitute for an argument.

Bottom percentile reading comprehension

I never said his experience makes what he's saying more valid. I said you're a retard for saying

You don't have the experience, expertise, or evidence to prove me wrong.

when he works as an actual cosmetic chemist - and so has more experience and expertise in the field than any of us.

Rather you're the one insisting they're more credible for having experience and expertise.

Follow your own advice;

Get off your high horse.

You're talking nonsense, everyone knows you're talking nonsense.

 

[GreenHat500]

But what about just simply taking a lot of vitamin-A supplements? Wouldn't that do a similar thing to low dose Accutane?

 

[Deleted member 5349]

Retin A+Doxycycline is a better combo imo. Far less toxic and nearly just as effective. You should only be taking accutane if your acne is severe and nothing else works

 

[CopingForLife]

I was getting al excited about the wonders of isotretinoin until I read benignice's comments about it.

 

[Deleted member 4053]

Diferin mogs Accutane to hell and back, and doesn't close growth plates.

 

[OBE]

JFL and not being able to get glowing skin already with Retin-A.

If retinoids don’t work to keep your skin acne/wrinkle-free and glowing then blame your shitty genetics for needing Accutane to achieve what others do with Retin-A.

 

[balding17yomanletcel]

tretinoin mogs

 

[Theonewhowillascend]

Just stunt your growth theory

Not in the 99% precent using it

 

[Deleted member 275]

Will ignore and keep using tretinoin.

 

[GreenHat500]

JFL and not being able to get glowing skin already with Retin-A.

If retinoids don’t work to keep your skin acne/wrinkle-free and glowing then blame your shitty genetics for needing Accutane to achieve what others do with Retin-A.

The people who have moderate or severe acne have longer telomeres. Their skin ages better etc... Why do you think Pitt aged so well even though he smoked and drank every single freaking day from like 20 years old? Cuz he was an acnecel in youth.

 

[FutureMogger]

The people who have moderate or severe acne have longer telomeres. Their skin ages better etc... Why do you think Pitt aged so well even though he smoked and drank every single freaking day from like 20 years old? Cuz he was an acnecel in youth.

JFL YEA having acne is great it gives you forever young skin lmao

 

[GreenHat500]

JFL YEA having acne is great it gives you forever young skin lmao

The people who never get acne in their life usually get the harshest wrinkles as they age.

 

[OBE]

The people who have moderate or severe acne have longer telomeres. Their skin ages better etc... Why do you think Pitt aged so well even though he smoked and drank every single freaking day from like 20 years old? Cuz he was an acnecel in youth.

I had moderate acne all my life until 18 and I solved it with Epiduo then continued to use Retin A, if you can solve it using topicals then just do so instead of getting on Accutane

 

[Deleted member 2205]

isotretinoin isn't a replacement for tretinoin lol