[Motivation] My ru58841 just came in the mail.

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I ordered 5 grams of it on Sunday. I'm about to mix 3 grams of it with my minoxidil should last me about 4 months. I will include progress pictures to see if I can fix my temporal balding(I'm Norwood 2). So my current hair loss prevention regiment is minoxidil mixed with ru58841, ketoconazole shampoo and micro-needling every 10 days using dr pen. This shit is great for any baldcel that wants to start roiding, using creatine or wants to raise their dht naturally without the Norwood reaper raping his hairline.
 
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JellyBelly

Clab my belly and it turns jelly
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40253
 

NickGurr

200 ng/dl HIGH T BEAST
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I got the raw powder and I'm mixing it with minoxidil
prepare for shedding and bloat like you've never seen, also from my research it seems that some of the RU actually gets absorbed into the bloodstream so it will have some overall antiandrogenic effects too
 

CupOfCoffee

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prepare for shedding and bloat like you've never seen, also from my research it seems that some of the RU actually gets absorbed into the bloodstream so it will have some overall antiandrogenic effects too
Some antiandrogenic systemic effects isn't as bad as destroying your DHT and chemically cuckolding yourself
 

Zeta ascended

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GL

keep in mind this will anger the Norwood Reaper and once you stop it's possible he will punish you by adding 3 points to your current Norwood level
I plan on using it long term until better solutions come out or hair becomes useless to me in my 40s.

This is what happens when you stop taking ru58841 the reaper was really angry
40303
 

BornAgainChad

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prepare for shedding and bloat like you've never seen, also from my research it seems that some of the RU actually gets absorbed into the bloodstream so it will have some overall antiandrogenic effects too
The amount that gets absorbed is so miniscule that it has virtually zero effects systematically. The circulating androgens out-compete the miniscule amounts of this chemical for the androgen receptor.
 

NickGurr

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The amount that gets absorbed is so miniscule that it has virtually zero effects systematically. The circulating androgens out-compete the miniscule amounts of this chemical for the androgen receptor.
It's not minuscule at all, especially with ethanol in the mix

And its an antiandrogen exactly because it competes with the androgens in your body
 

BornAgainChad

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It's not minuscule at all, especially with ethanol in the mix
It breaks down before it goes any further than your scalp. The chemical isn't very stable and has a really short half-life when not bound to a receptor or when it's not being refrigerated. That's why RU58841 suppliers recommend keeping it in a cool, dark place and using it quickly when it's constituted.

Even if it made it into your blood, the small amount that did would quickly break down. It's probably the PH profile that breaks it down, but it's just a theory that I came up with.

And its an antiandrogen exactly because it competes with the androgens in your body
But the amount of androgens are so high compared to the chemical that testosterone is far more likely to bind to the AR than RU58841.
 

NickGurr

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It breaks down before it goes any further than your scalp. The chemical isn't very stable and has a really short half-life when not bound to a receptor or when it's not being refrigerated. That's why RU58841 suppliers recommend keeping it in a cool, dark place and using it quickly when it's constituted.

Even if it made it into your blood, the small amount that did would quickly break down. It's probably the PH profile that breaks it down, but it's just a theory that I came up with.


But the amount of androgens are so high compared to the chemical that testosterone is far more likely to bind to the AR than RU58841.
IDK where the fuck you got your info from, I can barely find 2-3 legit papers on it
 

BornAgainChad

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IDK where the fuck you got your info from, I can barely find 2-3 legit papers on it
RU-59416 has very low affinity for the androgen receptor.[8]

Some sellers of the site said to keep this chemical refrigerated until use, which means that the chemical isn't very stable when constituted. This obviously translates to a much shorter shelf life, especially if it's exposed to light.

I'm not completely pulling this stuff out of my ass.
 

NickGurr

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RU-59416 has very low affinity for the androgen receptor.[8]

Some sellers of the site said to keep this chemical refrigerated until use, which means that the chemical isn't very stable when constituted. This obviously translates to a much shorter shelf life, especially if it's exposed to light.

I'm not completely pulling this stuff out of my ass.
I was thinking about the metabolite RU 56279 but just read a paper saying only 1% gets metabolized so I guess I'm wrong
 

Sasaz2

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prepare for shedding and bloat like you've never seen, also from my research it seems that some of the RU actually gets absorbed into the bloodstream so it will have some overall antiandrogenic effects too
Is it the ru or the minox that make the bloat and the shedding?
Is Ru effective without minox?
 

Sasaz2

Patrick Batemancel
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Both (reports from users, not norwooding yet so didnt look into them that well) and yes
Fck there is nothong that dont cause bloat
I would rather have my legs paralised than have bloat as a side effect
 

NickGurr

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Fck there is nothong that dont cause bloat
I would rather have my legs paralised than have bloat as a side effect
I dont know by which mechanisms it causes bloat (if it truly does) so I can't help with it sorry

Norwood reaper spares no one...
 

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