Test levels don't matter for building muscle - how androgen receptors respond to Test matters the most to building muscle (LOW-Tcels GTFIH Lifefuel)

[DrTony]

It's interesting if they are just born with a complete lack of the myostatin gene (does this produce any other distinct phenotypes besides excess muscle growth?), inherit certain rare SNP for the myostatin gene or they acquire somehow (environment) hypermethylated version of an otherwise normal myostatin gene resulting in downregulated myostatin rna/protein expression. I am 100% sure that myostatin is a small piece of the puzzle in general.

 

[Extra Chromosome]

A lot is not currently understood about myostatin and various other factors. As Dr Tony puts it, there is much undiscovered.

also its not necessarily the case that they do not produce any myostatin at all, it could just be to a lesser degree than most individuals. Expression can also be tissue specific, so while it might be true that if you inhibited myostatin systemically you might eventually end up with brittle tendons, it doesn't necessarily follow that genetic freaks with low myostatin expression in their muscle also have weak tendons. If you look at most of the BBing elite before they started lifting, theres rarely any obvious indication that they are gifted in this regard and yet in practice it is obvious that some individuals are capable of producing a great degree of muscularity that other individuals simply cannot, despite the same training methods, the same (or even more) drug use, the same dietary habits etc.

Yup, thanks for the response.

It's interesting if they are just born with a complete lack of the myostatin gene (does this produce any other distinct phenotypes besides excess muscle growth?), inherit certain rare SNP for the myostatin gene or they acquire somehow (environment) hypermethylated version of an otherwise normal myostatin gene resulting in downregulated myostatin rna/protein expression. I am 100% sure that myostatin is a small piece of the puzzle in general.

Agreed tbh ngl.
Will continue my research then boyo buckos.