Guide THE ULTIMATE PCT SUPPLEMENT(HPTA RESTORATION)

JustBeCurry

JustBeCurry

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Im gonna run it as stand alone as many have done on roiding forums and submit blood works. Meanwhile I came across this stuff called Letro XT the contents of it are. @JustBeCurry can u tell me about this coz I know jack shit and u've researched alot. I am indeed mirin ur hard work. Thanks
View attachment 715997
has the same stuff as novedex xt except androsta-3,5-diene-7,17-dione which is just an aromatase inhibitor so it should have the same effects as novedex xt besides the extra aromatase inhibition which might even be good in some cases, put please if you do take it post your bloods here before and after bro
 
sloopnoob

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has the same stuff as novedex xt except androsta-3,5-diene-7,17-dione which is just an aromatase inhibitor so it should have the same effects as novedex xt besides the extra aromatase inhibition which might even be good in some cases, put please if you do take it post your bloods here before and after bro
I will indeed post bloods since it goat shit on its own from what I think, but shipping is gonna take time I ordered something from US before and never received it in 3 months. But Predator Nutrition has so I can order from UK. Can you post the study which you used to show baseline and after hormonal levels?
 
JustBeCurry

JustBeCurry

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I will indeed post bloods since it goat shit on its own from what I think, but shipping is gonna take time I ordered something from US before and never received it in 3 months. But Predator Nutrition has so I can order from UK. Can you post the study which you used to show baseline and after hormonal levels?
https://pubmed.ncbi.nlm.nih.gov/17460335/ this study was done on the original novedex xt with ATD and 3-OHAT, which the new novedex does have two compounds related to ATD and claims to function similarly if not better, but still take the results in this study with a grain of salt
 
EternalLearner

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https://pubmed.ncbi.nlm.nih.gov/17460335/ this study was done on the original novedex xt with ATD and 3-OHAT, which the new novedex does have two compounds related to ATD and claims to function similarly if not better, but still take the results in this study with a grain of salt
Saw this study and its crazy. Did u see the possible side effects according to FDA? probably unfounded speculation, still sounds bad
 
EternalLearner

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Also if I could give some own ideas: there are some ATD prohormones which are still legal, maybe check that
 
gaymidget

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Is the normal available novaldex already the novaldex XT or do I have to specifically buy that one?
 
Vista

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Is the normal available novaldex already the novaldex XT or do I have to specifically buy that one?
It depends, check the ingredients of it
 
Vista

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what dosage was used in the studies?
 
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Toremifene is the ultimate PCT. Vastly superior to nolvadex and clomid.
 
Pubertymaxxingcel

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u need to be like 170 iq to even comprehend 190 to understand this. i have no idea what ur saying. u need some pictures fam cuz this is japanese in statistics class for me lol
Right like what the fuck is he talking about
 
EternalLearner

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the first sentence makes no sense, antagonism doesnt lower the amount of estrogen lmfao.. it actually increases it. please learn more about basic endocrinology terms and concepts. trust me clomid / nolva mogs..
Im not a big fan of most antagonists but i like the idea of a t booster OCT, u think i could just use this by itself? Sounds not bad ngl
 
TITUS

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PCT is HCG, novaldex and clomid. Forget about jewish scams like this one, why the fuck is this even stickied.
 
Lev Peshkov

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yo man bumoing have some questons ded srs
 
Mog and magog

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Let me preface this by saying please do your own research before you take anything.
scroll down for tldr and the stack

Article on bodybuilding.com with all the information mentioned in this thread including studies:

Technical Stuff
A brief summary of what the HPTA is, how it works, and why you do not want to be shutting it down:

Endogenous testosterone production(testosterone made inside your body) is governed by the HPTA(Hypothalamus-Pituitary-Testes-Axis). The hypothalamus releases a hormone called GnRH(or LH-releasing hormone); the hypothalamus maintains homeostatic control so you do not want to be fucking up the hypothalamus or any related part of the HPTA. The GnRH then goes to the pituitary gland to produce two other hormones LH(Luteinizing Hormone) and FSH(Follicle-Stimulating Hormone), which then the two hormones go the testes, and finally, you get testosterone synthesis and sperm production. The HPTA and the GnRH, LH, and FSH produced from it regulates the amount of testosterone, androstenediol, and DHEA in your body. If your HPTA produces extra GnRH, LH, and FSH you also get all the anabolic things like testosterone, and that is exactly why you don't want to it to crash from early steroid use and/or shitty PCT.

Why do you get side effects from steroids and the key to fixing the HPTA:

Most people know the estrogen-related side effects of steroids and why you absolutely do not want them. There are actually two negative feedback loops controlling the HPTA, the estrogen negative feedback loop, and the lesser-known androgen negative feedback loop. When too much estrogen interacts with the estrogen receptors of the hypothalamus, there's a negative feedback loop where the gland thinks there must be too much testosterone too, causing loss of testosterone or even shutdown. The hypothalamus also has androgen receptors, when it senses that there is too many androgens it causes a decrease or shutdown in GnRH release. This is probably why your balls shrink on steroids and you lose sexual function.

Common PCT and its faults:

Normal PCT would be something like Clomid, an AI(Anastrolzole is the one we're going to be talking about), and HCG. Clomid is actually a very weak estrogen that blocks more powerful estrogens from merging with the hypothalamic estrogen receptors, this causes the hypothalamus to detect less estrogen and to increase GnRH release. Anastrozole is an aromatase enzyme inhibitor that decreases conversions of androgens into estrogens, which leads to a decrease in total circulatory estrogen and has some benefits of HPTA regeneration. HCG or Human Chorionic Gonadotropin in males has been shown to mimic LH, so it leads to the direct stimulation of the testes resulting in a minimal increase in sperm production and a significant increase in testicular testosterone production.

Addressing the androgen negative feedback loop:

Until pretty recently hypothalamus-specific androgen inhibition wasn't possible, there are some 'new' compounds that have been introduced.
3-OHAT: 6,17-dioxo-etiocholene-3-ol or 3-OHAT is a metabolite of a popular anti-aromatase supplement 4-androstene-36,17-trione(AT). 3-OHAT has a longer half-life than AT, and it is also a non-androgenic aromatase inhibitor(very important for the androgen negative feedback loop). 3-OHAT is a fast-acting long-term destroyer of the estrogen negative feedback loop, and consequently increases testosterone
ATD:3,17-dioxo-etiochol-1,4,6-triene or ATD is 2.8 times more powerful than AT and more powerful than 3-OHAT in a different way. In vitro studies have shown ATD to be a powerful androgen receptor blocker of the hypothalamus, but not of peripheral androgen receptors. Basically, this means it blocks the androgen negative feedback loop caused by the hypothalamus, so in turn GnRH release increases resulting in decreased estrogen production while increasing natural testosterone production. If the dosages of 3-OHAT and ATD are combined correctly there is an average increase in bioavailable testosterone of up to 400% and a direct decrease in estrogens of an average 50%, and this is proven by studies.

Real-world testing:

Eight human test subjects were used in a study on ATD and 3-OHAT, four were placebo base-line and the other four received a blend consisting of 3-OHAT and ATD.

Placebo Group:
No significant changes in total or free testosterone and estradiol(obvious)

Subject 1 (24yr old male:
Pre-testing-
Total T: 350ng/dl
Free T: 83.00pg/ml
Estradiol: 39pg/ml
14 Days-
Total T: 1803ng/dl
Free T: 522.90pg/ml
Estradiol:27pg/ml
42 Days-
Total T: 2895ng/dl
Free T: 839.20pg/ml
Estradiol: <20
View attachment 699487View attachment 699488

Subject 2 (33yr old male):
Pre-testing-
Total T: 538ng/dl
Free T: 129.0pg/ml
Estradiol: 30pg/ml
14 Days-
Total T: 998ng/dl
Free T: 233.0pg/ml
Estradiol: 22pg/ml
42 Days-
Total T: 1416ng/dl
Free T: 421.3pg/ml
Estradiol: 22pg/ml
View attachment 699490View attachment 699491

Subject 3 (25yr old male):
Pre-testing-
Total T: 555ng/dl
Free T: 104.00pg/ml
Estradiol: <20
14 Days-
Total T: 1624ng/dl
Free T: 405.7pg/ml
Estradiol: <20
42 Days-
Total T: 1837ng/dl
Free T: 405.7pg/ml
Estradiol: <20
View attachment 699492View attachment 699493

Subject 4 (51yr old male):
Pre-testing-
Total T: 584ng/dl
Free T: 13.40ng/dl
Estradiol: 47pg/ml
14 Days-
Total T: 851ng/dl
Free T: 26.10ng/dl
Estradiol <20
42 Days-
Total T: 875ng/dl
Free T: 30.30ng/dl
Estradiol: <20
View attachment 699496View attachment 699499

What does this mean for looksmax.me and roidcels:

So basically we need to take something with 3-OHAT and ATD to successfully prevent androgen and estrogen negative feedback loops. There used to exist products with actual 3-OHAT and ATD, but most of them have been recalled, as well as ATD being banned as a supplement. Unless if you have some contacts then getting real 3-OHAT and ATD is a no-go for most of us.

Actual important bit
The ultimate PCT:

Novedex XT, this is all you need. A previous version of this Novedex XT included real 3-OHAT and ATD, but since it's banning the formula has been updated. The new versions formula includes 3b-hydroxy-androsta-1,4,6-triene-17-one, 3b-hydroxy-androsta-4,6-diene-17-one, and androsta-3,5-diene-7,17-dione.
Novedex XT does not have any androgenic metabolites that could cause HPTA suppression. 3b-hydroxy-androsta-4,6-diene-17-one is the so called 'ATD imposter' due to its structure and mechanism of action and it is a steroidal aromatase inhibitor, permanently binding to the aromatase enzyme. 3,5-dien-7,17-dione is another potent aromatase inhibitor.

TLDR; Nolvadex XT is a PCT that will help restore HPTA function and does not have any suppression to it.

Thanks for reading if you read all this. TAG YOUR FRIENDS BRO
REMINDER: I'M NOT ADVOCATING YOU TRY THIS OR SHILLING FOR THIS PRODUCT, IT SEEMS PROMISING BUT I MYSELF HAVE NOT TRIED IT, BUT WILL IN THE FUTURE

@Lev Peshkov
@xefo69
@ItisOver
only people I know who to tag lmao
highest iq thread
 
GarouTheIncel

GarouTheIncel

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Let me preface this by saying please do your own research before you take anything.
scroll down for tldr and the stack

Article on bodybuilding.com with all the information mentioned in this thread including studies:

Technical Stuff
A brief summary of what the HPTA is, how it works, and why you do not want to be shutting it down:

Endogenous testosterone production(testosterone made inside your body) is governed by the HPTA(Hypothalamus-Pituitary-Testes-Axis). The hypothalamus releases a hormone called GnRH(or LH-releasing hormone); the hypothalamus maintains homeostatic control so you do not want to be fucking up the hypothalamus or any related part of the HPTA. The GnRH then goes to the pituitary gland to produce two other hormones LH(Luteinizing Hormone) and FSH(Follicle-Stimulating Hormone), which then the two hormones go the testes, and finally, you get testosterone synthesis and sperm production. The HPTA and the GnRH, LH, and FSH produced from it regulates the amount of testosterone, androstenediol, and DHEA in your body. If your HPTA produces extra GnRH, LH, and FSH you also get all the anabolic things like testosterone, and that is exactly why you don't want to it to crash from early steroid use and/or shitty PCT.

Why do you get side effects from steroids and the key to fixing the HPTA:

Most people know the estrogen-related side effects of steroids and why you absolutely do not want them. There are actually two negative feedback loops controlling the HPTA, the estrogen negative feedback loop, and the lesser-known androgen negative feedback loop. When too much estrogen interacts with the estrogen receptors of the hypothalamus, there's a negative feedback loop where the gland thinks there must be too much testosterone too, causing loss of testosterone or even shutdown. The hypothalamus also has androgen receptors, when it senses that there is too many androgens it causes a decrease or shutdown in GnRH release. This is probably why your balls shrink on steroids and you lose sexual function.

Common PCT and its faults:

Normal PCT would be something like Clomid, an AI(Anastrolzole is the one we're going to be talking about), and HCG. Clomid is actually a very weak estrogen that blocks more powerful estrogens from merging with the hypothalamic estrogen receptors, this causes the hypothalamus to detect less estrogen and to increase GnRH release. Anastrozole is an aromatase enzyme inhibitor that decreases conversions of androgens into estrogens, which leads to a decrease in total circulatory estrogen and has some benefits of HPTA regeneration. HCG or Human Chorionic Gonadotropin in males has been shown to mimic LH, so it leads to the direct stimulation of the testes resulting in a minimal increase in sperm production and a significant increase in testicular testosterone production.

Addressing the androgen negative feedback loop:

Until pretty recently hypothalamus-specific androgen inhibition wasn't possible, there are some 'new' compounds that have been introduced.
3-OHAT: 6,17-dioxo-etiocholene-3-ol or 3-OHAT is a metabolite of a popular anti-aromatase supplement 4-androstene-36,17-trione(AT). 3-OHAT has a longer half-life than AT, and it is also a non-androgenic aromatase inhibitor(very important for the androgen negative feedback loop). 3-OHAT is a fast-acting long-term destroyer of the estrogen negative feedback loop, and consequently increases testosterone
ATD:3,17-dioxo-etiochol-1,4,6-triene or ATD is 2.8 times more powerful than AT and more powerful than 3-OHAT in a different way. In vitro studies have shown ATD to be a powerful androgen receptor blocker of the hypothalamus, but not of peripheral androgen receptors. Basically, this means it blocks the androgen negative feedback loop caused by the hypothalamus, so in turn GnRH release increases resulting in decreased estrogen production while increasing natural testosterone production. If the dosages of 3-OHAT and ATD are combined correctly there is an average increase in bioavailable testosterone of up to 400% and a direct decrease in estrogens of an average 50%, and this is proven by studies.

Real-world testing:

Eight human test subjects were used in a study on ATD and 3-OHAT, four were placebo base-line and the other four received a blend consisting of 3-OHAT and ATD.

Placebo Group:
No significant changes in total or free testosterone and estradiol(obvious)

Subject 1 (24yr old male:
Pre-testing-
Total T: 350ng/dl
Free T: 83.00pg/ml
Estradiol: 39pg/ml
14 Days-
Total T: 1803ng/dl
Free T: 522.90pg/ml
Estradiol:27pg/ml
42 Days-
Total T: 2895ng/dl
Free T: 839.20pg/ml
Estradiol: <20
View attachment 699487View attachment 699488

Subject 2 (33yr old male):
Pre-testing-
Total T: 538ng/dl
Free T: 129.0pg/ml
Estradiol: 30pg/ml
14 Days-
Total T: 998ng/dl
Free T: 233.0pg/ml
Estradiol: 22pg/ml
42 Days-
Total T: 1416ng/dl
Free T: 421.3pg/ml
Estradiol: 22pg/ml
View attachment 699490View attachment 699491

Subject 3 (25yr old male):
Pre-testing-
Total T: 555ng/dl
Free T: 104.00pg/ml
Estradiol: <20
14 Days-
Total T: 1624ng/dl
Free T: 405.7pg/ml
Estradiol: <20
42 Days-
Total T: 1837ng/dl
Free T: 405.7pg/ml
Estradiol: <20
View attachment 699492View attachment 699493

Subject 4 (51yr old male):
Pre-testing-
Total T: 584ng/dl
Free T: 13.40ng/dl
Estradiol: 47pg/ml
14 Days-
Total T: 851ng/dl
Free T: 26.10ng/dl
Estradiol <20
42 Days-
Total T: 875ng/dl
Free T: 30.30ng/dl
Estradiol: <20
View attachment 699496View attachment 699499

What does this mean for looksmax.me and roidcels:

So basically we need to take something with 3-OHAT and ATD to successfully prevent androgen and estrogen negative feedback loops. There used to exist products with actual 3-OHAT and ATD, but most of them have been recalled, as well as ATD being banned as a supplement. Unless if you have some contacts then getting real 3-OHAT and ATD is a no-go for most of us.

Actual important bit
The ultimate PCT:

Novedex XT, this is all you need. A previous version of this Novedex XT included real 3-OHAT and ATD, but since it's banning the formula has been updated. The new versions formula includes 3b-hydroxy-androsta-1,4,6-triene-17-one, 3b-hydroxy-androsta-4,6-diene-17-one, and androsta-3,5-diene-7,17-dione.
Novedex XT does not have any androgenic metabolites that could cause HPTA suppression. 3b-hydroxy-androsta-4,6-diene-17-one is the so called 'ATD imposter' due to its structure and mechanism of action and it is a steroidal aromatase inhibitor, permanently binding to the aromatase enzyme. 3,5-dien-7,17-dione is another potent aromatase inhibitor.

TLDR; Nolvadex XT is a PCT that will help restore HPTA function and does not have any suppression to it.

Thanks for reading if you read all this. TAG YOUR FRIENDS BRO
REMINDER: I'M NOT ADVOCATING YOU TRY THIS OR SHILLING FOR THIS PRODUCT, IT SEEMS PROMISING BUT I MYSELF HAVE NOT TRIED IT, BUT WILL IN THE FUTURE

@Lev Peshkov
@xefo69
@ItisOver
only people I know who to tag lmao
link ? i found one source but its from a supplement store so i doubt its the real deal
 

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