audimax
Adidasmaxxed Chad
- Joined
- Dec 8, 2018
- Posts
- 3,263
- Reputation
- 3,664
This study found a significant increase in Vasopressin by those consuming a high-Protein diet
"Vasoactive hormonal response to two levels of dietary protein intake was studied in seven healthy adult volunteers. The subjects were randomly placed on a 2-g.kg-1.day-1 (high) or 0.55-g.kg-1.day-1 (low) diet using a crossover design and were studied on the morning of the 5th day and again after 24 h of indomethacin treatment. Plasma renin activity (PRA), aldosterone, vasopressin, and urinary excretion of 6-ketoprostaglandin F1 alpha (PGF1 alpha) were significantly higher on the high-protein diet despite constancy of body weight, blood pressure, pulse, urinary sodium and potassium excretion, and plasma amino acid levels. After treatment with cyclooxygenase inhibitor indomethacin, 6-keto-PGF1 alpha excretion was equalized, but the elevated PRA and aldosterone levels persisted on the high-protein diet, suggesting that PRA and aldosterone elevations do not depend entirely on prostanoid release. We conclude that chronic augmentation of dietary protein intake is accompanied by alterations of vasoactive hormones, which persist for up to 10 h postprandially and are independent of elevated plasma amino acid levels. Such hormonal alterations may mediate some of the dietary protein-mediated changes in renal hemodynamics."
In another study, people with kidney desease were put on a low-osmolar diet (low sodium, low urea, low protein (0.8g/kg bodyweight)). They found a significant decrease in Vasopressin after following the diet.
"We developed a step-wise dietary intervention that led to significant reduction in vasopressin in ADPKD patients. Furthermore, this intervention led to reduction in water required for vasopressin reduction."
"However, adherence to high fluid intake is difficult to maintain in clinical practice(12, 13). Part of the difficulty in sustaining a low AVP level with daily water ingestion is the consumption of a high osmolar diet (diet high in protein and salt), which stimulates AVP secretion to maintain water homeostasis(14). To address the adherence challenges associated with a fluid-based treatment, we have combined a low osmolar diet with adjusted water intake, with the goal of lowering the amount of water intake needed to reduce AVP secretion."
TL;DR: Vasopressin is one of the hormones responsible for water retention and why you look bloated in the morning. Implement a low-sodium low-protein diet to reduce water retention. If you keep eating high protein, up the water consumption by a lot.
"Vasoactive hormonal response to two levels of dietary protein intake was studied in seven healthy adult volunteers. The subjects were randomly placed on a 2-g.kg-1.day-1 (high) or 0.55-g.kg-1.day-1 (low) diet using a crossover design and were studied on the morning of the 5th day and again after 24 h of indomethacin treatment. Plasma renin activity (PRA), aldosterone, vasopressin, and urinary excretion of 6-ketoprostaglandin F1 alpha (PGF1 alpha) were significantly higher on the high-protein diet despite constancy of body weight, blood pressure, pulse, urinary sodium and potassium excretion, and plasma amino acid levels. After treatment with cyclooxygenase inhibitor indomethacin, 6-keto-PGF1 alpha excretion was equalized, but the elevated PRA and aldosterone levels persisted on the high-protein diet, suggesting that PRA and aldosterone elevations do not depend entirely on prostanoid release. We conclude that chronic augmentation of dietary protein intake is accompanied by alterations of vasoactive hormones, which persist for up to 10 h postprandially and are independent of elevated plasma amino acid levels. Such hormonal alterations may mediate some of the dietary protein-mediated changes in renal hemodynamics."
In another study, people with kidney desease were put on a low-osmolar diet (low sodium, low urea, low protein (0.8g/kg bodyweight)). They found a significant decrease in Vasopressin after following the diet.
"We developed a step-wise dietary intervention that led to significant reduction in vasopressin in ADPKD patients. Furthermore, this intervention led to reduction in water required for vasopressin reduction."
"However, adherence to high fluid intake is difficult to maintain in clinical practice(12, 13). Part of the difficulty in sustaining a low AVP level with daily water ingestion is the consumption of a high osmolar diet (diet high in protein and salt), which stimulates AVP secretion to maintain water homeostasis(14). To address the adherence challenges associated with a fluid-based treatment, we have combined a low osmolar diet with adjusted water intake, with the goal of lowering the amount of water intake needed to reduce AVP secretion."
TL;DR: Vasopressin is one of the hormones responsible for water retention and why you look bloated in the morning. Implement a low-sodium low-protein diet to reduce water retention. If you keep eating high protein, up the water consumption by a lot.
Last edited: