mathis
Zephir
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Here’s everything to know abt this new compound. Not a steroid and not AFD approved.
**How Myostatin Inhibitors Work**:
Myostatin is a protein that regulates muscle growth. It acts as a natural brake, limiting the size and strength of muscles. Myostatin inhibitors block the action of myostatin, making it easier for muscles to grow.
**Action mechanism:**
- Myostatin inhibitors bind to myostatin and prevent it from attaching to its receptors on muscle cells.
- This blocks the signaling cascade that leads to the breakdown of muscle proteins.
- Muscle protein synthesis is then increased, which allows muscles to grow more quickly.
**Comparison with trenbolone (tren) because its what yall want :
Trenbolone is an anabolic steroid that has effects similar to myostatin inhibitors. It increases muscle protein synthesis and decreases muscle protein breakdown.
**Efficiency:**
- Myostatin inhibitors and trenbolone are both effective for gaining muscle mass.
- Studies have shown that myostatin inhibitors can increase muscle mass by 10-20% in a few months.
- Trenbolone can increase muscle mass by 20-30% in a few months.
**Side effects:**
- Trenbolone has more serious side effects than myostatin inhibitors.
- Side effects of Trenbolone may include acne, aggression, high blood pressure, and liver damage.
- Side effects of myostatin inhibitors are usually mild and include muscle pain, headache, and fatigue.
As you can see, Risk/benefit ratio is better with myostatin inhibitor
Current synthetic myostatin inhibitor :
**1. Myostatin-Fc (ACE-031):**
- Developed by Acceleron Pharma and Amgen.
- Phase 2 clinical trials for Duchenne muscular dystrophy (DMD).
- Also in trials for amyotrophic lateral sclerosis (ALS) and rheumatoid arthritis.
**2. BMS-986165:**
- Developed by Bristol-Myers Squibb.
- Phase 2 clinical trials for DMD.
- Showed promising results in increasing muscle mass and strength.
**3. LY2484936:**
- Developed by Eli Lilly and Company.
- Phase 1 clinical trials for DMD.
- Well tolerated and showed increased muscle protein synthesis.
**4. AMG 745:**
- Developed by Amgen.
- Phase 1 clinical trials for DMD.
- Showed increased muscle mass and strength in animal models.
**5. SRK-015:**
- Developed by Sorrento Therapeutics.
- Phase 1 clinical trials for DMD.
- Showed inhibition of myostatin and increased myogenesis in animal models.
**Other synthetic myostatin inhibitors:**
- Enobosarm (ostarine)
- Andarine
-Ligandrol
- S-23
-YK-11
This thread isnt complete yet. I am still making in depth rechearch
@Rigged @Osie @mogpending @SkullDynamics ( sorry if i forgot someone )
**How Myostatin Inhibitors Work**:
Myostatin is a protein that regulates muscle growth. It acts as a natural brake, limiting the size and strength of muscles. Myostatin inhibitors block the action of myostatin, making it easier for muscles to grow.
**Action mechanism:**
- Myostatin inhibitors bind to myostatin and prevent it from attaching to its receptors on muscle cells.
- This blocks the signaling cascade that leads to the breakdown of muscle proteins.
- Muscle protein synthesis is then increased, which allows muscles to grow more quickly.
**Comparison with trenbolone (tren) because its what yall want :
Trenbolone is an anabolic steroid that has effects similar to myostatin inhibitors. It increases muscle protein synthesis and decreases muscle protein breakdown.
**Efficiency:**
- Myostatin inhibitors and trenbolone are both effective for gaining muscle mass.
- Studies have shown that myostatin inhibitors can increase muscle mass by 10-20% in a few months.
- Trenbolone can increase muscle mass by 20-30% in a few months.
**Side effects:**
- Trenbolone has more serious side effects than myostatin inhibitors.
- Side effects of Trenbolone may include acne, aggression, high blood pressure, and liver damage.
- Side effects of myostatin inhibitors are usually mild and include muscle pain, headache, and fatigue.
As you can see, Risk/benefit ratio is better with myostatin inhibitor
Current synthetic myostatin inhibitor :
**1. Myostatin-Fc (ACE-031):**
- Developed by Acceleron Pharma and Amgen.
- Phase 2 clinical trials for Duchenne muscular dystrophy (DMD).
- Also in trials for amyotrophic lateral sclerosis (ALS) and rheumatoid arthritis.
**2. BMS-986165:**
- Developed by Bristol-Myers Squibb.
- Phase 2 clinical trials for DMD.
- Showed promising results in increasing muscle mass and strength.
**3. LY2484936:**
- Developed by Eli Lilly and Company.
- Phase 1 clinical trials for DMD.
- Well tolerated and showed increased muscle protein synthesis.
**4. AMG 745:**
- Developed by Amgen.
- Phase 1 clinical trials for DMD.
- Showed increased muscle mass and strength in animal models.
**5. SRK-015:**
- Developed by Sorrento Therapeutics.
- Phase 1 clinical trials for DMD.
- Showed inhibition of myostatin and increased myogenesis in animal models.
**Other synthetic myostatin inhibitors:**
- Enobosarm (ostarine)
- Andarine
-Ligandrol
- S-23
-YK-11
This thread isnt complete yet. I am still making in depth rechearch
@Rigged @Osie @mogpending @SkullDynamics ( sorry if i forgot someone )