Does retinol shorten telomere ?

[maxmax901]

So is it true or not ?
How can a side effect so important can be completely forgotten on the internet ? I don't see any debunk or anyone trying to say it's true

Nobody talks about that possible side effect, or when someone does, they try to sell retinol mixed with telomerase jfl

For people who don't know, the idea is :
Since retinol increase cell turnover, and that according to Hayflick Limit, you cells can only divide 50 times in average in your entire lifetime, this would mean that you won't have enough skin cells when youre older, because you would have used most of them during youth (20 to 40 yo)

 

[Shekelberg]

Despite the Hayflick doctrine being dogmatic at its core, retinol increases differentiation and turns cells away from water logging, sensless divisions and overtly keratinisation.
Retinol would be antithetical to cell division if used right

 

[BasedPsychiatrist]

No, not really.

Be it retinol or forms of tretinoin. I mean, you are not wrong in the sense that those may impact the lenght of telomeres. The thing is, in proper doses, they may stimulate apoptosis of some tumor cell types, rather than have a significant impact on healthy cells. The are no critical studies that show any meaningful risks. To the contrary, in fact.
It's critical for skincare and treat is as such.

 

[Lawton88]

So is it true or not ?
How can a side effect so important can be completely forgotten on the internet ? I don't see any debunk or anyone trying to say it's true

Nobody talks about that possible side effect, or when someone does, they try to sell retinol mixed with telomerase jfl

For people who don't know, the idea is :
Since retinol increase cell turnover, and that according to Hayflick Limit, you cells can only divide 50 times in average in your entire lifetime, this would mean that you won't have enough skin cells when youre older, because you would have used most of them during youth (20 to 40 yo)

You would be alright if your stem cells stay working properly. A lot of people get a lot of inflammation when older that makes a lot of stem cells not function properly.

 

[maxmax901]

Despite the Hayflick doctrine being dogmatic at its core, retinol increases differentiation and turns cells away from water logging, sensless divisions and overtly keratinisation.
Retinol would be antithetical to cell division if used right

It's either bs or i'm too low IQ to understand what you just said

 

[BasedPsychiatrist]

And to add my few cents. The Hayflick's view is just a model that does not take many things into consideration. Don't stress it out. You probably do much more things daily that ages you more than tretinoin ever would.

If telomeres were the root cause of aging, those who eat excessive amounts of telomerase would outlive all of us.

 

[czwarty]

I asked this in college to prof. who specialised in aging research, it was told to me that it won't due to increased telomerase plus the simple fact that basal cells don't follow Hayflick's
So we're safe, if it was to actually age organism due to how much it exfoliates you'd see insane aging in very short time of use, which obviously is not the case

 

[BasedPsychiatrist]

It's either bs or i'm too low IQ to understand what you just said

He's right. Aging is much, much more complex.

 

[czwarty]

It's either bs or i'm too low IQ to understand what you just said

Hayflick's limit is the limit of how many times the cell can multiply before it "runs out of steam". However, this is for differentiated cells, and basal cells (cells that are made to constantly multiply and produce new cells, like in skin which constantly dies and exfoliates) do not work according to Hayflick's limit (because that's what they're made for)

 

[Brootal]

yeah retinol gives u down syndrome bro stick to using your feces for anti aging

 

[maxmax901]

Hayflick's limit is the limit of how many times the cell can multiply before it "runs out of steam". However, this is for differentiated cells, and basal cells (cells that are made to constantly multiply and produce new cells, like in skin which constantly dies and exfoliates) do not work according to Hayflick's limit (because that's what they're made for)

I asked this in college to prof. who specialised in aging research, it was told to me that it won't due to increased telomerase plus the simple fact that basal cells don't follow Hayflick's
So we're safe, if it was to actually age organism due to how much it exfoliates you'd see insane aging in very short time of use, which obviously is not the case

Lifefuel to get these answers
I was going to start it at 19 yo but maybe tought it would be too young

 

[Shieda_Kayn]

I asked this in college to prof. who specialised in aging research, it was told to me that it won't due to increased telomerase plus the simple fact that basal cells don't follow Hayflick's
So we're safe, if it was to actually age organism due to how much it exfoliates you'd see insane aging in very short time of use, which obviously is not the case

Based iq.