MECHANISM AND POSSIBLE CURE TO BALDING

[Deleted member 6273]

I'm going to keep the thread short cause of the average attention span here and cba spending hours writing a thread here.

Most probable Mechanism of balding
Dependent on both DHT and mechanical tension (affects DHT levels in the scalp)
"chronic scalp tension transmitted from the galea aponeurotica induces an inflammatory response in androgenic alopecia-prone tissues; (2) dihydrotestosterone increases in androgenic alopecia-prone tissues as part of this inflammatory response; and (3) dihydrotestosterone does not directly miniaturize hair follicles. Rather, dihydrotestosterone is a co-mediator of tissue dermal sheath thickening, perifollicular fibrosis, and calcification – three chronic, progressive conditions concomitant with androgenic alopecia progression. These conditions remodel androgenic alopecia-prone tissues – restricting follicle growth space, oxygen, and nutrient supply – leading to the slow, persistent hair follicle miniaturization characterized in androgenic alopecia"

for anyone interested in delving deeper into why I believe this to be true

Involvement of Mechanical Stress in Androgenetic Alopecia

Androgenetic alopecia (AGA) is a frequent disorder characterized by progressive hair miniaturization in a very similar pattern among all affected men. The pathogenesis is related to androgen-inducible overexpression of transforming growth factor β-1 ...

www.ncbi.nlm.nih.gov

A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors

Androgenic alopecia, also known as pattern hair loss, is a chronic progressive condition that affects 80% of men and 50% of women throughout a lifetim…

www.sciencedirect.com

Possible cure
So we are already aware of how limiting/decreasing DHT through oral and topical medications like finasteride can positively affect hair growth, now what happens if we reduce scalp tension.

Botox
This a simple explanation of how botox will affect hair growth.

"Conceptually, Botox “loosens” the scalp, reducing pressure on the perforating vasculature, thereby increasing blood flow and oxygen concentration. The enzymatic conversion of testosterone to dihydrotestosterone is oxygen dependent. In low-oxygen environments, the conversion of testosterone to dihydrotestosterone is favored; whereas in high-oxygen environments, more testosterone is converted to estradiol.4 Blood flow may therefore be a primary determinant in follicular health. Strategically placed Botox injections appear able to indirectly modify this variable, resulting in reduced hair loss and new hair growth in some men with androgenetic alopecia."

scientific proof:

Treatment of male pattern baldness with botulinum toxin: a pilot study - PubMed

Treatment of male pattern baldness with botulinum toxin: a pilot study

pubmed.ncbi.nlm.nih.gov

A Pilot Study to Evaluate Effectiveness of Botulinum Toxin in Treatment of Androgenetic Alopecia in Males

Androgenetic alopecia is a common form of alopecia with multifactorial etiology. Finasteride and minoxidil are approved by the FDA for the treatment of androgenetic alopecia. Balding scalp is believed to have relative microvascular insufficiency. Blood ...

www.ncbi.nlm.nih.gov

Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia

<i>Background</i>. Androgenetic alopecia (AGA) represents the most frequent clinical complaint encountered by dermatologists and is characterized by a progressive miniaturization of the hair follicle. However, the efficacy and safety of current medical treatment remain limited, and more...

www.hindawi.com

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onlinelibrary.wiley.com

NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals

NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary

www.jwatch.org

specialists providing the procedure:

Botox for hair restoration. BOTOX Hair Growth | Sani Hair Institute

BOTOX injections into the scalp have been proven to relax the scalp muscles, enhance blood flow and increase the delivery of nutrients to the hair thus increasing hair density.

saniprphairmd.com

New Hair Loss Treatment with BOTOX

Beverly Hills, CA (PRWEB) February 4, 2009 -- Preliminary findings have shown that BOTOX® injections into the scalp may effectively delay hair loss and even

www.prweb.com

 

[Deleted member 6273]

@Baldingman1998 @SubhumanCurrycel @LastHopeForNorman @eduardkoopman @Patient A

 

[Deleted member 7076]

the more mechanisms we can address, the better

 

[LastHopeForNorman]

 

[SubhumanCurrycel]

@Baldingman1998 @SubhumanCurrycel @LastHopeForNorman @eduardkoopman @Patient A

Thanks this was a good read
Not sure if this fully applies to me tho cos my hairloss was from chemo

 

[LastHopeForNorman]

Thanks this was a good read
Not sure if this fully applies to me tho cos my hairloss was from chemo

tbh After botox your hair should be better because of better nutrient transfer.

 

[SubhumanCurrycel]

tbh After botox your hair should be better because of better nutrient transfer.

What about corticosteroid injections, my dermatologist was thinking of testing it out does the same thing I’m pretty sure.

 

[LastHopeForNorman]

Why no one do it in Europe for fuck sake

 

[LastHopeForNorman]

What about corticosteroid injections, my dermatologist was thinking of testing it out does the same thing I’m pretty sure.

I dont know what corticosteroid injections is
So i cant tell

 

[Patient A]

Nice, as a NW0 bro, I will add this to my arsenal if I ever deviate from NW0 to NW1.5

 

[Patient A]

What about corticosteroid injections, my dermatologist was thinking of testing it out does the same thing I’m pretty sure.

Go for botox tbh

 

[SubhumanCurrycel]

Go for botox tbh

How different is it?
I’ll ask him about it next appointment see what he thinks

 

[LastHopeForNorman]

Go for botox tbh

Not feasible at the moment for most people tbh
You need 2 to 3 sessions of botox in year. flying to america 3 times will be pretty expensive for some guy
@SubhumanCurrycel

 

[TheEndHasNoEnd]

i believe the tension in the galea part of the scalp is caused by headshape. a long head horizontally from the side profile would be more prone to frontal balding. my dad is like the highest norwood and a long head from side profile. i have androgenic alopecia confirmed by dermatologists and scalp biopsy, but its on the sides of my head and not front. i have a wide neurocranium but its horizontally short from the side profile. i wonder if hypertrophying the temples with chewing can transfer the pressure away fron the galea.

 

[SubhumanCurrycel]

Not feasible at the moment for most people tbh
You need 2 to 3 sessions of botox in year. flying to america 3 times will be pretty expensive for some guy
@SubhumanCurrycel

Is Botox expensive?

 

[SubhumanCurrycel]

i believe the tension in the galea part of the scalp is caused by headshape. a long head horizontally from the side profile would be more prone to frontal balding. my dad is like the highest norwood and a long head from side profile. i have androgenic alopecia confirmed by dermatologists and scalp biopsy, but its on the sides of my head and not front. i have a wide neurocranium but its horizontally short from the side profile. i wonder if hypertrophying the temples with chewing can transfer the pressure away fron the galea.

Are biopsy’s useful and diagnosing hairloss and potential for regrowth?
just got one done still waiting for results

 

[TheEndHasNoEnd]

Are biopsy’s useful and diagnosing hairloss and potential for regrowth?
just got one done still waiting for results

idk what it does besides detecting what u have

 

[SubhumanCurrycel]

idk what it does besides detecting what u have

6 years and I still haven’t being diagnosed with a definitive form or cause of hairloss.
These stitches on my scalp better tell me something because if it’s another “I don’t know” diagnosis from another doctor I’m going ER

 

[LastHopeForNorman]

Is Botox expensive?

No
But flying to america 3 times in a year is

 

[diggbicc]

This thread has been made many times by @AutisticBeaner and some others, legit but reposted

https://looksmax.org/threads/homo-s...loss-dht-and-craniofacial-development.302068/

 

[TheEndHasNoEnd]

6 years and I still haven’t being diagnosed with a definitive form or cause of hairloss.
These stitches on my scalp better tell me something because if it’s another “I don’t know” diagnosis from another doctor I’m going ER

ur a diagnosed jaw slayer bhai

 

[SubhumanCurrycel]

ur a diagnosed jaw slayer bhai

Unfortunately jaw is cope its all about the hair

 

[SubhumanCurrycel]

This thread has been made many times by @AutisticBeaner and some others, legit but reposted

https://looksmax.org/threads/homo-s...loss-dht-and-craniofacial-development.302068/

ur a high IQ user explain why im a bald subhuman pls

 

[TheEndHasNoEnd]

Unfortunately jaw is cope its all about the hair

cope

 

[Deleted member 6273]

This thread has been made many times by @AutisticBeaner and some others, legit but reposted

https://looksmax.org/threads/homo-s...loss-dht-and-craniofacial-development.302068/

Not really the same thing though similar and the point of the thread is more focused on the potential cure of balding through easing mechanical tension and I provided multiple studies particularly on the role of botox in curing hairloss which i've never seen being comprehensively done before.

 

[SubhumanCurrycel]

cope
View attachment 1037518

still has a hairline would be invisible to women if his head was clean skin bald

 

[Deleted member 6273]

This thread has been made many times by @AutisticBeaner and some others, legit but reposted

https://looksmax.org/threads/homo-s...loss-dht-and-craniofacial-development.302068/

I'm also a bit skeptical on the role of cranoifacial development and hairloss because there are many examples of people with excellent craniofacial development who still end up losing all their hair for example Boris Kodjoe.

 

[Deleted member 6273]

Pmub

 

[aleksandr]

DDi

I'm also a bit skeptical on the role of cranoifacial development and hairloss because there are many examples of people with excellent craniofacial development who still end up losing all their hair for example Boris Kodjoe.
View attachment 1037520View attachment 1037521

Did he lose his hair or just have really high hairline?

 

[Deleted member 6273]

DDi

Did he lose his hair or just have really high hairline?

He lost it all

 

[Deleted member 643]

Interesting. Thanks, OP.

 

[Deleted member 6273]

UP

 

[lasthope]

stop the scalp tension theory pls

hairtransplant wouldn't work if this theory would be true

 

[Deleted member 6273]

stop the scalp tension theory pls

hairtransplant wouldn't work if this theory would be true

I just provided multiple scientific studies to prove my point, what exactly do you disagree with be specific

 

[lasthope]

I just provided multiple scientific studies to prove my point, what exactly do you disagree with be specific

with HT you take DHT resistant folicle and place it on the place where your hair felt off
This folicle will stay there. when you theory would be true it should fall off (since scap tension and shit is the same)

 

[Deleted member 6273]

with HT you take DHT resistant folicle and place it on the place where your hair felt off
This folicle will stay there. when you theory would be true it should fall off (since scap tension and shit is the same)

In no part of my arguement did I say that all follicles are the same, I know there are DHT resistant follicles at the back of the head. My theory is basically saying that higher scalp tension causes more inflamation in the scalp DHT is an anti inflamatory androgen so it's directed to the scalp. This in turn leads to minitiaurisation of the non resistant hair follicles at the top of the scalp i.e norwooding

 

[grimy]

Good read, thanks for sharing. It matches my own experience also. My temporalis muscles protrude excessively when I eat due to my bite being slightly off. Often times it feels like I worked out my head just by eating. I wonder if this tension has accelerated my norwood.

 

[eduardkoopman]

Hairloss ddue to dht levels.

And

Hairloss due to less scalp blood flow.

2 different causes of balding.
Needing different treatments?

 

[Deleted member 6273]

Hairloss ddue to dht levels.

And

Hairloss due to less scalp blood flow.

2 different causes of balding.
Needing different treatments?

I mean yeah but in the OP I explained I was talking about androgenic alopecia

 

[Deleted member 6273]

B

 

[Deleted member 6273]

b

 

[Deleted member 6273]

 

[Deleted member 6273]

bump

 

[AlexAP]

stop the scalp tension theory pls

hairtransplant wouldn't work if this theory would be true

with HT you take DHT resistant folicle and place it on the place where your hair felt off
This folicle will stay there. when you theory would be true it should fall off (since scap tension and shit is the same)

There have been all sorts of experiments with humans and animals, here is one conclusion:

"The takeaways: scalp hair follicles adapt to growth rates set by their surrounding environment. Thus, scalp hair follicles can be influenced by the location in which they are transplanted."

Do Hair Transplants Debunk The Scalp Tension-Hair Loss Hypothesis?

Does a tight scalp cause pattern hair loss? This question recently resurfaced in hair loss forums… sparking heated debate from scalp tension supporters and opposers. The supporters: scalp tension must contribute to hair loss. Why? Because

perfecthairhealth.com

 

[Deleted member 20056]